Medicinal Chemistry and Structure-Activity RelationshipsDate Added: 3/23/2007 5:34:00 PM
Last Updated: 11/5/2008 1:23:00 PM
Description of projects available to graduate students:
We pursue several collaborative studies in the development of experimental therapeutics for cancer, degenerative diseases, and radiation mitigation and prevention. Lead structures are optimized using modern medicinal chemistry techniques. ChemInformatics tools are used to build virtual libraries and select analogues based on three-dimensional fingerprints coding for functional groups, number of H-bond acceptors, aromatic bonds, the ratio of rotatable bonds vs total bonds, and others. Targeted libraries are used to generate SAR and identify backup candidates.
Techniques graduate student will learn:
Synthetic Organic Chemistry
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