Aaron Bell, PhD
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Program:
Cellular and Molecular Pathology
Graduated:
5/1999
Mentor:
Dr. Reza Zarnegar
Thesis:
Transgenic Models of Hepatocyte Growth Factor Gene Regulation and Function
Previous Institutions Attended:
University of Pittsburgh, BS in Biochemistry
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I am an Assistant Professor in the Department of Pathology at the University of Pittsburgh School of Medicine. I work as an independent faculty member with a research lab focused on the study of transcription factors in liver cell growth, regeneration, differentiation and cancer. I also maintain teaching responsibilities in the Interdisciplinary Biomedical Graduate Program. You can view my webpage at http://path.upmc.edu/personnel/Faculty/Bell.htm.
Fellowships, Awards, Promotions:
Pathology Postdoctoral Research Training Grant July, 2000
Pathology Postdoctoral Research Training Grant July, 2001
NIH-NIDDK NRSA-F32 Fellowship Sept., 2001-2003
JHF/CORO Health Sciences Fellowship Summer 2003
Promoted to Faculty 11/2005
Recent Publications:
Wang X, DeFrances MC, Dai Y, Pediaditakis P, Johnson C, Bell A, Michalopoulos GK, Zarnegar R. A mechanism of cell survival: sequestration of Fas by the HGF receptor Met.
Mol Cell. Feb;9(2):411-21 (2002).
Kolher, C, Bell, AW, Bowen, WC, Monga, SP, Michalopoulos, GK. Expression of Notch-1 and its ligand Jagged-1 in rat liver during liver regeneration. Hepatology 39(4), 1056-65 2004.
Bell, A. W. and Michalopoulos, G. K. Phenobarbital Induces Nuclear Expression of HNF4 in mouse and rat hepatocytes independent of CAR and PXR. Hepatology. Jul;44(1):186-94 2006.
Publications while a graduate student at Pitt:
Bell, A. W., Chen, Q., DeFrances, M. C., Michalopolous, G. K., Zarnegar, R. The five amino acid-deleted isoform of hepatocyte growth factor promotes carcinogenesis in transgenic mice. Oncogene 18, 887-895 (1999).
Bell, A. W., Jiang, J. G., Chen, Q., Liu, Y., Zarnegar, R.The upstream regulatory regions of the hepatocyte growth factor gene promoter are essential for its expression in transgenic mice. J Biol Chem. 273, 6900-8 (1998)
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