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Research Interests- Development of a mucosal vaccines for HIV using the SIV:macaque model for AIDS
- Pathogenesis and transmission of SIV across mucosal portals of entry
- Characterization of reservoirs of SIV in chronically infected macaques and development of effective methodologies for therapy
- Genetic adaptation of SIV among susceptible species
- Genetic basis of disease resistance in macaques infected with SIV
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Selected Publications- Bissel SJ, Wang G, Bonneh-Barkay D, Starkey A, Trichel AM, Murphey-Corb M, Wiley CA. Systemic and brain macrophage infection in Simian Immunodeficiency Virus Encephalitis.J Virol. 2008 Mar 12; [Epub ahead of print]
- Fallert BA, Poveda S, Schaefer TM, Pfeifer ME, Sanghavi SK, Watkins SC, Murphey-Corb MA, Tarwater PM, Kirschner DE, Reinhart TA. Virologic and immunologic events in hilar lymph nodes during simian immunodeficiency virus infection: development of polarized inflammation. J Acquir Immune Defic Syndr. 2008 Jan 1;47(1):16-26.
- Taber R, Rajakumar PA, Fuller DH, Trichel AM, Dowling P, Meleason D, Amedee A, Murphey-Corb M.Effects of monotherapy with (R)-9-(2-phosphonylmethoxypropyl)adenine (PMPA) on the evolution of a primary Simian immunodeficiency virus (SIV) isolate. Virology. 2006 Oct 10;354(1):116-31.
- Steckbeck JD, Grieser HJ, Sturgeon T, Taber R, Chow A, Bruno J, Murphy-Corb M, Montelaro RC, Cole KS. Dynamic evolution of antibody populations in a rhesus macaque infected with attenuated simian immunodeficiency virus identified by surface plasmon resonance. J Med Primatol. 2006 Aug;35(4-5):248-60
- Bissel SJ, Wang G, Trichel AM, Murphey-Corb M, Wiley CA. Longitudinal analysis of monocyte/macrophage infection in simian immuno-deficiency virus-infected, CD8+ T-cell-depleted macaques that develop lentiviral encephalitis. Am J Pathol. 2006 May;168(5):1553-69.
Complete Publication Listing
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Other
Links
MMG Faculty Webpage
University of Pittsburgh |
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Michael Anne Murphey-Corb, Ph.D., Professor
| Office:
E1252 Biomedical Science Tower |
| Lab:E1252 Biomedical Science Tower |
| Phone:412-648-9462 |
| Fax: 412-648-1448
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mcorb@pitt.edu
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Academic Affiliations- Adjunct Professor
Infectious Disease & Microbiology
GSPH
- Professor
Dept. of Microbiology and Molecular Genetics
- Director, Primate Research Facility for
Infectious Diseases
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Education- 1969 B.S. Medical Technology
Northeast Louisiana University
Monroe, LA
- 1969 M.T. ASCP
Ochsner Foundation Hospital
New Orleans, LA
- 1977 M.S. Microbiology & Immunology
Louisiana State University
New Orleans, LA
- 1980 Ph.D. Microbiology & Immunology
Louisiana State University
New Orleans, LA
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Lab Personnel
Research Assistant Professors:
Deb Fuller, Ph.D., Toshi Kodama, DVM, Ph.D.
Research Associates:
Premi Rajakumar, Ph.D., Julia Myaundi, DVM
Lab Technicians:
Heather Michael, Eric Seabright, Brendon Wahlberg, Jenny Che
MVM Graduate Student:
Rachel Taber
Administrative Assistant:
Emily Gress
Phone: 412/967-6591
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