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Faculty Expand All | Collapse All Karen M. Arndt [+][-] Associate Professor mechanisms of eukarayotic transciptional regulation Homepage Ivet Bahar [+][-] Professor Modeling and simulation of protein complexes Homepage Nathan Bahary [+][-] Assistant Professor to combine the power and insight of vertebrate development to elucidate basic molecular processes Homepage Jeffrey L Brodsky [+][-] Professor Mechanism and Action of Molecular Chaperones Homepage J. Richard Chaillet [+][-] Associate Professor Stem cell biology Homepage Preet M. Chaudhary [+][-] Professor Regulation of NF-kappaB Pathway and Apoptosis; Signaling via members of the Tumor Necrosis Factor Receptor Family Homepage Tao Cheng [+][-] Associate Professor stem cell biology; transplantation biology; and cancer biology Homepage Paula R. Clemens [+][-] Associate Professor Viral vector gene transfer to muscle Homepage Neal A. DeLuca [+][-] Professor Regulation of herpes simplex virus gene expression; design of HSV vectors for gene therapy Homepage Anette Duensing [+][-] Assistant Professor molecular biology of gastrointestinal stromal tumors (*GISTs) and mechanism of action of targeted therapies Homepage Stefan Duensing [+][-] Associate Professor The laboratory is interested in the molecular mechanisms that cause genomic instability in cancer. The human papillomavirus (HPV) has been proven a particularly useful model to study this problem Homepage Miguel Estevez [+][-] Assistant Professor Primarily focused on using the invertebrate, Caenorhabditis elegans, to model human neurologic diseases. For example, human clinical genetics led to the identification of mutations in a P/Q-type calcium channel gene as the cause of a rare dominant form o Homepage Alfred L. Fisher [+][-] Assistant Professor biology of aging; C. elegans genetics; stress response pathways; genomics and microarrays; protein chemistry Homepage James L. Funderburgh [+][-] Associate Professor Roles for extracellular matrix in cellular responses during wound healing and tissue regeneration; Properties and bioengineering applications of adult stem cells in the eye Homepage Ole Gjoerup [+][-] Assistant Professor Analysis of cell signaling, genomic instability and cancer pathways using SV40 as a model system and with particular focus on the Bub1 spindle checkpoint kinase Homepage Joseph C. Glorioso [+][-] Professor Herpes simplex virus, latency, glycoprotein, pathogenesis and use in human gene therapy Homepage Fred L. Homa [+][-] Associate Professor Human herpes viruses that are responsible for a variety of clinically significant diseases Homepage Gregg E. Homanics [+][-] Associate Professor Production of animal models of human disease Homepage Rebecca P. Hughey [+][-] Associate Professor Apical targeting and membrane trafficking in polarized epithelial cells: focus on the transmembrane human mucin MUC1 and the ectoenzyme gamma-glutamyltranspeptidase Homepage Neil A. Hukriede [+][-] Assistant Professor Embryonic patterning, kidney organogenesis, xenopus laevis, zebrafish Homepage Naftali Kaminski [+][-] Associate Professor interstitial lung diseases, pulmonary fibrosis, systems biology, biomarkers, genomics, microarrays, matric metalloproteases, mRNA Homepage Saleem A. Khan [+][-] Professor Molecular biology and pathogenesis of human papillomaviruses (HPVs); Role of microRNAs in HPV-associated cancers, and in aging; DNA helicases; Replication, maintenance and transfer of drug resistance and virulence plasmids of Staphylococcus aureus and Bac Homepage Jes K. Klarlund [+][-] Associate Professor Growth factor signaling Homepage Mark E. Lowe [+][-] Professor The role of pancreatic lipases in dietary fat digestion Homepage Bruce A. McClane [+][-] Professor Biochemical structure and molecular actions of bacterial toxins; bacterial pathogenicity Homepage Timothy A. Mietzner [+][-] Associate Professor Mechanism by which Neisseria gonorrhoeae obtain growth-essential iron from the human host Homepage Christine A. Milcarek [+][-] Professor Immunoglobulin gene expression and differentiation Homepage A. Paula Monaghan-Nichols [+][-] Assistant Professor Genetic analysis of vertebrate CNS development Homepage Ronald C. Montelaro [+][-] Professor Patrick Moore [+][-] Professor KSHV interactions with the host cells and the use of molecular biology techniques to discover new oncogenic viruses Homepage Sidney M. Morris [+][-] Professor Transcriptional and metabolic responses to cytokines and inflammation Homepage Laura J. Niedernhofer [+][-] Associate Professor Investigating how DNA damage promotes aging and cancer using mouse models of human DNA repair deficiency syndromes Homepage Robert M. O'Doherty [+][-] Assistant Professor Mechanisms of insulin resistance in obesity/NIDDM Homepage Kyle Orwig [+][-] Assistant Professor Research focuses on the biological activity and functional genetic characterization of male germline stem cells. Research on these adult tissue stem cells that are at the foundation of spermatogenesis has implications for male reproduction & infertility. Homepage Edward V. Prochownik [+][-] Professor Proto-oncogenes in differentiation; oncoprotein-DNA interaction; signal transduction Homepage Baskaran Rajasekaran [+][-] Associate Professor DNA damage-induced cell signaling cell cycle regulation, DNA repair and growth control Homepage Paul D. Robbins [+][-] Professor Gene therapy to facilitate islet transplantation: Insulin-dependent diabetes melllitus (IDDM) is characterized by destruction of the insulin-producing pancreatic beta-cell Homepage Guillermo G. Romero [+][-] Associate Professor Signal transduction mechanisms associated to the activation of cellular phospholipases Homepage David Roodman [+][-] Professor Cellular and molecular events controlling the formation and activity of osteoblasts from bone in normal and paathologic states Homepage William Saunders [+][-] Associate Professor Kinetochores and cell cycle control ; chromosomal segregation defects in oral cancer Homepage Martin C. Schmidt [+][-] Associate Professor Our research focuses on the Snf1 and AMP-activated protein kinase (AMPK). These kinases are key players in a signal transduction pathway activated by energy stress and glucose limitation in all eukaryotic cells; target for treatment of type 2 diabetes Homepage Donald K. Scott [+][-] Associate Professor The nutritional regulation of cellular phenotype; how nutrients, especially glucose, alter the regulation of genes to change the phenotype of cells Homepage Gary Silverman [+][-] Professor Exploring the role of how serpins protect cells from promiscuous exogenous and endogenous peptidases. Using a comparative genomics approach, we have isolated serpin genes in humans, mice and nematodes that block cell death. Homepage Thomas E Smithgall [+][-] Professor Tyrosine kinase signalling pathways in normal development, cancer and HIV/AIDS Homepage Richard A. Steinman [+][-] Associate Professor Investigation of p-53 like molecules and cell cycle regulation in leukemogenesis and in stem cells Homepage Michael Tsang [+][-] Assistant Professor Research is directed toward elucidating genetic mechanisms controlling early patterning events in the vertebrate embryo, particularly in the role of Firoblast Growth Factors Homepage Ben Van Houten [+][-] Professor mitochondrial dysfunction in cancer and neurodegenerative diseases; structure-function studies of DNA repair proteins Jerry Vockley [+][-] Professor Biochemical and molecular basis of inborn errors of metabolism Homepage William H. Walker [+][-] Associate Professor Gene regulation in Sertoli cells that mediates development and differentiation of male germ cells. Homepage Yong Wan [+][-] Assistant Professor The role of ubiquitin-dependent proteolysis in biological regulation; the control of cell cycle progression by proteolytic regulation. Homepage Xiangyun Wei [+][-] Assistant Professor Study how retinal epithelial polarity contributes to the formation of the layered cellular structure of the mature retina; investigate how cell-cell adhesion molecules play a role in retinal pattern formation Homepage Gutian Xiao [+][-] Associate Professor study of signal transduction pathways in immunity and tumorigenesis, particularly autophagy and NF-kB. Homepage
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