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Faculty Expand All | Collapse All Gerard L. Apodaca [+][-] Professor Regulation of endocytic traffic by the exocyst complex; stretch-regulated exocytosis/endocytosis in bladder umbrella cells Homepage Meir Aridor [+][-] Associate Professor The molecular basis for COP II mediated cargo selection, export, transport to the Golgi. The regulation of cargo degradation in the ER. Biogenesis of CFTR in the early secretory pathway. Biosynthetic transport mechanisms in primary neurons. Homepage Jeffrey L Brodsky [+][-] Professor Protein biogenesis and degradation Homepage Michael B. Butterworth [+][-] Assistant Professor Regulation of epithelial ion channels by trafficking and recycling mechanisms Homepage Jennifer C. Condon [+][-] Assistant Professor The study of maternal-fetal signaling during pregnancy to understand the molecular pathways of labor; the role of nuclear receptors in mammalian testicular and ovarian development Homepage Daniel C. Devor [+][-] Professor Structure-function studies on the trafficking, assembly, and regulation of calcium-dependent potassium channels Homepage Peter F. Drain [+][-] Associate Professor Understanding insulin secretion, dopamine secretion, and structure-mechanism relations underlying the ATP-inhibited potassium (KATP) channel response to physiologically important ligands, in degenerative diseases Homepage Raymond A. Frizzell [+][-] Professor Epithelial ion transport and cell biology; the molecular mechanisms responsible for defects in epithelial electrolyte secretion and absorption in cystic fibrosis and renal disease. Homepage James L. Funderburgh [+][-] Professor Roles for extracellular matrix in cellular responses during wound healing and tissue regeneration; Properties and bioengineering applications of adult stem cells in the eye Homepage Arjumand Ghazi [+][-] Assistant Professor Molecular genetics of aging in C. elegans Homepage David J. Hackam [+][-] Professor The role of the innate immune system in the development of systemic sepsis; characterization and therapeutic potential of intestinal stem cells Homepage Kenneth R. Hallows [+][-] Associate Professor Coupling of epithelial ion transport to cellular metabolic status via AMP-activated kinase. Homepage Yang Hong [+][-] Assistant Professor The use of genetic, cell biological and biochemical approaches in Drosophila to study the development of cell polarity Homepage Rebecca P. Hughey [+][-] Professor Assembly and proteolytic activation of the epithelial sodium channel Homepage John P. Johnson [+][-] Professor Epithelial Na+ Channel; aldosterone Homepage Thomas R. Kleyman [+][-] Professor Structure, function, and regulation of epithelial sodium channels; epithelial potassium channels Homepage Adam V Kwiatkowski [+][-] Assistant Professor Organization and dynamics of actin networks Homepage Sanford Leuba [+][-] Associate Professor chromatin structure and dynamics is of major importance in regulating transcription, replication and repair; single molecule approaches to dynamic protein/nucleic acid interactions Homepage Rama K. Mallampalli [+][-] Professor mammalian phospholipid metabolism in models of inflammatory lung injury Homepage Sandra A. Murray [+][-] Professor Molecular mechanisms regulating gap junction protein trafficking; the role of signal transduction and cell-cell communication in the regulation of cell proliferation, transformation,secretion, motility, and endocrine response Homepage Nuria Pastor-Soler [+][-] Assistant Professor Epithelial proton secretion in the male reproductive tract Homepage David H. Perlmutter [+][-] Professor and Chair cellular pathobiology of alpha-1-antitrypsin deficiency; intracellular accumulation of aggregation-prone proteins Homepage Tony M. Plant [+][-] Professor Testicular stem cell renewal and spermatogenesis in primates Homepage Aleksandar Rajkovic [+][-] Associate Professor Reproductive genetics Homepage Kathleen D. Ryan [+][-] Associate Professor Control of puberty in mammals Homepage Abhiram Sahu [+][-] Associate Professor The neurobiology of feeding, obesity and diabetes, particularly mechanisms of leptin and insulin signaling in the hypothalamus Homepage Guy Salama [+][-] Professor Elucidating the mechanisms responsible for the initiation and termination of cardiac arrythmias Homepage Gerald P. Schatten [+][-] Professor Molecular basis of reproduction and development; Stem cells and transplantation Homepage Gary Silverman [+][-] Professor Exploring the role of how serpins protect cells from promiscuous exogenous and endogenous peptidases. Using a comparative genomics approach, we have isolated serpin genes in humans, mice and nematodes that block cell death. Homepage Alexander D. Sorkin [+][-] Professor and Chair to understand how endocytosis and post-endocytic trafficking regulates function(s) of the transmembrane proteins, such as receptors and transporters Homepage Claudette M. St. Croix [+][-] Assistant Professor Identification of post-translational protein modifications induced by nitric oxide (NO) related species in pulmonary endothelium, and determination of the physiological consequences of these events in vivo. Current studies concentrate on the zinc-binding. Homepage Donna Beer Stolz [+][-] Associate Professor Signal transduction pathways that regulate normal neovascularization in the regenerating of the liver Homepage Arohan Subramanya [+][-] Assistant Professor Regulation of thiazide-sensitive NaCl contransport, blood pressure and potassium homeostasis Homepage Nirmala Sundar Raj [+][-] Associate Professor molecular mechanisms of corneal morphogenesis, regeneration,and homeostasis Homepage Shivalingappa K. Swamynathan [+][-] Assistant Professor regulation of gene expression during ocular surface development and maintenance Homepage Agnieszka Swiatecka-Urban [+][-] Assistant Professor intracellular protein trafficking in human epithelial cells; specific focus on CFTR and nephrin Homepage Patrick H. Thibodeau [+][-] Assistant Professor Structure function relationships in membrane proteins; regulation of membrane protein biogenesis, recycling and degradation Homepage Linton M. Traub [+][-] Associate Professor Molecular dissection of the clathrin-coat assembly process and the role of clathrin-coated vesicles in intracellular membrane trafficking Homepage William H. Walker [+][-] Associate Professor Defining how the Sertoli cells translate hormone stimuli into alterations in gene expression that are required for male reproduction. Homepage Yong Wan [+][-] Associate Professor The role of ubiquitin-dependent proteolysis in biological regulation; the control of cell cycle progression by proteolytic regulation. Homepage Simon C. Watkins [+][-] Professor Development, assembly and integration of the dystrophin cytoskeleton and its potential role(s) in establishing and maintaining normal muscle function Homepage Ora A. Weisz [+][-] Professor Apical membrane targeting mechanisms in polarized epithelial cells Homepage David C. Whitcomb [+][-] Professor Genetics of acute and chronic pancreatitis and genetics of pancreatic cancer; Neurohormonal control of pancreatic exocrine secretion and pathophysiologic processes including the effects of alcohol and genetic predisposition; pancreatic physiology Homepage Christine C Wu [+][-] Associate Professor Membrane protein proteomics and mass spectrometry Anthony J. Zeleznik [+][-] Professor The physiology and cell biology of ovarian function Homepage
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