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Faculty
Expand All | Collapse All Elias Aizenman [+][-]
Professor
Cellular and molecular mechanisms of neuronal cell death
Homepage Daniel L. Altschuler [+][-]
Associate Professor
G-protein signaling mechanisms in mitogenesis and oncogenesis
Homepage Susan Amara [+][-]
Thomas Detre Professor and Chair
Major research efforts have focused on the structure, regulation and cellular physiology of two families of sodium-dependent neurotransmitter transporters: the biogenic amine and the excitatory amino acid carriers.
Homepage Christopher J. Bakkenist [+][-]
Assistant Professor
DNA damage signaling
Homepage Lori A Birder [+][-]
Associate Professor
Study a number of ion channel/receptor targets within the bladder epithelium and the possible role of the urothelium in urinary bladder function.
Homepage Alessandro Bisello [+][-]
Associate Professor
Structure, signalling and trafficking of G-protein-coupled receptors. Role of PTHrP in vascular remodeling and role of GLP-1 in pancreatic beta cell function
Homepage Robert A. Branch [+][-]
Professor
Drug metabolism
Homepage Thomas P. Conrads [+][-]
Associate Professor
Biological applications of mass spectrometry; proteonics; metabo (1/n); molecular mechanisms of cancer initiation, progression and metastais; interstitial cystitis; biomarker assay development using selected/multiple reaction monitoring mass spectrometry
Homepage Dennis P. Curran [+][-]
Professor
Natural products total synthesis, new synthetic methods, stereochemistry, radical chemistry, and fluorous chemistry
Homepage Billy W. Day [+][-]
Professor
Medicinal chemistry/ molecular pharmacology of microtubule perturbing agents and selective estrogen receptor modulators
Homepage Donald B. DeFranco [+][-]
Professor
Signal transduction and neurodegeneration
Homepage William C. deGroat [+][-]
Professor
Study of the autonomic mechanisms involved in the control of urogenital function
Homepage Julie Eiseman [+][-]
Associate Professor
Preclinical studies of potential anti-cancer agents, both in vitro and in vivo, and provides laboratory support for phase I clinical trials
Homepage John D. Fernstrom [+][-]
Professor
Control of neurotransmitter and neuropeptide synthesis and function
Homepage Bruce A. Freeman [+][-]
Professor and Chair
Cell Signaling; Redox Reactions
Homepage Peter A. Friedman [+][-]
Professor
Parathyroid hormone receptor trafficking, regulation, signaling.
Homepage Ferruccio Galbiati [+][-]
Associate Professor
Signal transduction mechanisms in muscular dystrophy and ageing/cancer
Homepage Jennifer Grandis [+][-]
Professor
Targeting signal transduction pathways in cancer
Homepage Angela M Gronenborn [+][-]
Professor
Biomolecular structure and its correlation to function in transcription factor complelxes, HIV-2 proteins and signaling proteins
Homepage Gregg E. Homanics [+][-]
Associate Professor
Application of transgenic technologies to investigate the molecular targets of ethanol and general anesthetics; production of animal models of human disease
Homepage John P. Horn [+][-]
Professor
Synaptic integration in sympathetic ganglia and in midbrain dopamine neurons.
Homepage Jeffrey Isenberg [+][-]
Associate Professor Edwin K. Jackson [+][-]
Professor
The physiology and pharmacology of endogenous modulators of growth, structure and function of cells in the heart, blood vessels and kidneys, with particular focus on adenosine, the renin-angiotensin soystem and estradiol metabolites
Homepage Yu Jiang [+][-]
Assistant Professor
Signaling mechanisms for cell growth control; Regulation of protein kinases and phosphatases
Homepage Daniel E. Johnson [+][-]
Associate Professor
Molecular signaling mechanisms that are important in the regulation and execution of apoptotic cell death; molecular mechanisms of hematopoietic cell differentiation; molecular mechanisms of hematopoietic cell differentiation
Homepage Valerian E. Kagan [+][-]
Professor
Nitric oxide interactions with cellular components, redox status during cellular injury and repair
Homepage Anthony John Kanai [+][-]
Assistant Professor
Roles of the urothelium, interstitial cells, afferent nerves and spontaneous bladder contractions in urinary incontinence. Use of B3 adrenergic agonists, P2Y6 antagonists and botulinum Toxin A as putative therapies.
Homepage Lawrence Kane [+][-]
Assistant Professor
Immunilogic function and signaling of TIM proteins
Homepage Judith Klein-Seetharaman [+][-]
Assistant Professor
Sequence-structure dynamics-function relationships in proteins, in particular membrane proteins and natively unfolded proteins. Specific interests in the mechanisms of signal transduction and protein folding/misfolding pathways.
Homepage Joan M. Lakoski [+][-]
Professor
Neuropharmacology of aging and serotonin receptors; mentoring and professional development
Homepage John S. Lazo [+][-]
Professor
Biological functions of protein phosphatases in normal and malignant cells; drug discovery; small molecule pharmacology
Homepage Edwin S. Levitan [+][-]
Professor
Regulation of ion-channels and peptide secretion
Homepage Michael T. Lotze [+][-]
Professor
role of the nuclear protein HMGB1 in promoting inflammation, mRNA role in regulating the translation of proteins in macrophages and other inflammatory cells
Homepage Patrick Pagano [+][-]
Associate Professor
development of peptic, viral and small molecular inhibitors of NADPH oxidases and reactive species in cardiovascular disease
Homepage Michael J. Palladino [+][-]
Assistant Professor
Combined molecular and genetic approach to identify key proteins required for neural maintenance with age and understand the role of these gene products in human disease conditions
Homepage Ruth G. Perez [+][-]
Assistant Professor
Molecular mechanisms of proteins implicated in neurodegenerative disease
Homepage Bruce R. Pitt [+][-]
Professor
Role of oxidants and nitric oxide in affecting pulmonary endothelial and vascular smooth muscle cell function.
Homepage Guillermo G. Romero [+][-]
Associate Professor
Regulation of phospholipase D by tyrosine kinase receptors
Homepage James R. Roppolo [+][-]
Research Assistant Professor
Autonomic nervous system control of bladder activity
Homepage Jill M. Siegfried [+][-]
Professor
Control of expression and mechanisms of cell signaling by peptide ligands and hormones, and their receptors, in lung cancer
Homepage Shivendra V. Singh [+][-]
Professor
Cancer chemoprevention using dietary and traditional medicine constituents; cell cycle regulation; apoptosis; in vivo models of cancer chemoprevention; immune response to dietary cancer chemopreventive agents
Homepage Thomas E Smithgall [+][-]
Professor
Chemical biology and drug discovery
Homepage Robert W. Sobol [+][-]
Assistant Professor
Research focuses on the role of DNA repair proteins in the repair of DNA damage induced by chemotherapeutic drugs and radiation, with an emphasis on the cell signaling and the cell survival pathways that are ingaged by such DNA damage.
Homepage Richard A. Steinman [+][-]
Associate Professor
Molecular controls of normal hematopoiesis and leukemogenisis; coupling of cell cycle and differentiation control
Homepage Pei Tang [+][-]
Associate Professor
Structural biology/computational biology/protein drug interactions/molecular mechanism of general anesthesia
Homepage Gonzalo E. Torres [+][-]
Assistant Professor
Cellular and molecular neuroscience
Homepage Ben Van Houten [+][-]
Professor
mitochondrial dysfunction in cancer and neurodegenerative diseases; structure-function studies of DNA repair proteins
Homepage Qiming Jane Wang [+][-]
Assistant Professor
Protein kinase D as a molecular target for prostate cancer; crosstalk between protein kinase D and insulin signaling and the relevance to type II diabetes
Homepage Zhou Wang [+][-]
Professor
Mechanism of androgen receptor intracellular trafficking in prostate cancer cells
Homepage Ronald Wetzel [+][-]
Professor
aggregate structure; fibril assembly and inhibition; the bases of aggregate cytotoxicity
Homepage Peter Wipf [+][-]
Professor
Medicinal chemistry, combinatorial synthesis for drug design
Homepage Wen Xie [+][-]
Associate Professor
Nuclear ormone receptor-mediated gene regulation and the implication of this regulation in liver diseases, cancer, obesity and diabetes
Homepage Yan Xu [+][-]
Professor
Gene and stem cell therapy in brain is chemical membrane protein structure by NMR
Homepage Jack C. Yalowich [+][-]
Associate Professor
Mechanisms of anticancer drug resistance; molecular pharmacology of DNA topoisomerase II inhibitors
Homepage Lin Zhang [+][-]
Assistant Professor
Genetic basis of differential responses to anticancer drugs and mechanisms of drug-induced apoptosis.
Homepage Michael J. Zigmond [+][-]
Professor
Synthesis and release of chemical neurotransmitters; etiology of neuropsychiatric disorders that involve dysfunctions of transmission, and the adaptive response to those dysfunctions
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