The Becker laboratory studies the molecular mechanisms regulating genetic and acquired cardiomyopathies to identify novel methods to prevent heart failure and sudden death. We utilize a variety of experimental systems which include animal model organisms, human induced pluripotent stem cell cardiomyocytes (iPS-CM) and human tissue samples.
Current projects are:
- MDM2-HIF signaling in pathological ventricular remodeling (NIH 1R01 HL167955)
- Cardiomyocyte selective modulation of natriuretic peptide signaling in cardiomyopathy (NIH 1R01 HL169784)
Website: https://beckerlab.pitt.edu/
The Becker laboratory studies the molecular mechanisms regulating genetic and acquired cardiomyopathies to identify novel methods to prevent heart failure and sudden death. We utilize a variety of experimental systems which include animal model organisms, human induced pluripotent stem cell cardiomyocytes (iPS-CM) and human tissue samples.
Current projects are:
- MDM2-HIF signaling in pathological ventricular remodeling (NIH 1R01 HL167955)
- Cardiomyocyte selective modulation of natriuretic peptide signaling in cardiomyopathy (NIH 1R01 HL169784)
Website: https://beckerlab.pitt.edu/