Development and application of Organs-on-a-Chip technologies to advance our understanding of human pathophysiology, accelerate drug discovery, and enable precision medicine, particularly in the context of pulmonary, vascular, immune, and rare diseases.
We apply a multidisciplinary strategy to design and develop biologically and clinically inspired technologies (such as Organs-on-Chips, Vaping Robot and 3D-Bioprinting) that enable us to elucidate cellular and molecular mechanisms that govern tissue pathology or offer protection during lung injury. Simply put, we emulate human lung biology and function at micro- and nano-scale dimensions to tackle unmet preclinical needs in pulmonary medicine.
Our research lies at the intersection of lung biology, immuno-microbiology, tissue microengineering, inhalation toxico-pathology, programming & AI, electrical & mechanical engineering, and systems biology. Ultimately, our goal is to discover novel druggable targets, develop candidate therapeutics, uncover personalized diagnostics and accurately mimic human-relevant pathophysiology using living and non-living engineered systems.