Our lab (jointly co-directed with Dr. Yuan Chang) seeks to identify new human cancer viruses and to understand how these viruses initiate cell transformation and tumorigenesis. To this end, we discovered the viruses causing Kaposi sarcoma (Kaposi sarcoma herpesvirus, KSHV) and Merkel cell carcinoma (Merkel cell polyomavirus, MCV) using molecular techniques. Our laboratory is currently seeking to new proteomic methods that may help inform us on the presence of undiscovered viruses in cancers thought to have an infectious etiology.
Dr. Moore's research interests involve examining viruses that cause human cancer. Together with Dr. Yuan Chang, who is also a Distinguished and American Cancer Society Professor of Pathology, he discovered two of the seven viruses causing human cancers (Kaposi sarcoma herpesvirus and Merkel cell polyomavirus). Their laboratory examines the basic biology of these viruses and seeks to develop new approaches to vaccinate against human viruses.