1. The Gomez lab is focused on studying the functional role of epigenetic and transcriptional mechanisms in controlling key properties of vascular smooth muscle cells (SMC) including cell differentiation, lineage memory and plasticity in the context of major cardiovascular diseases including atherosclerosis.
2. Control of smooth muscle cell differentiation and lineage memory; epigenetics/smooth muscle cell plasticity and atherosclerosis; epigenetic and inflammation in atherosclerosis.
| The molecular mechanisms controlling vascular smooth muscle cell phenotype and behavior during vascular development and diseases. Current projects include studies to determine: 1) Epigenetic alterations in major cardiovascular diseases including peripheral artery disease and aortic aneurysm and their consequence on smooth muscle cell phenotype, 2) identification of new functional non-coding RNA in SMC, and 3) relationship between mechanotransduction and epigenetic programming. |
The Gomez lab is focused on studying the functional role of epigenetic and transcriptional mechanisms in controlling key properties of vascular smooth muscle cells (SMC) including cell differentiation, lineage memory and plasticity in the context of major cardiovascular diseases including atherosclerosis.
Control of smooth muscle cell differentiation and lineage memory; epigenetics/smooth muscle cell plasticity and atherosclerosis; epigenetic and inflammation in atherosclerosi