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Program 1
Program 1 Research Interests
Telomeres in human health and disease
Program 1 Faculty Information
Program 2
Program 2 Faculty Information
Program 2 Research Interests
My research focuses on understanding the role of telomere length in human health and disease. Telomeres are caps on the ends of each of chromosomes and shorten as we age. My current interest is exploring the mechanisms by which telomere dysfunction causes age-related lung diseases including pulmonary fibrosis and emphysema. We also conducting research to understand how telomeres are maintained in cancer cells. Our lab uses a number of approaches to explore that pathogenesis of short-telomere mediated disease including genetics, cell biology, and animal models. We hope these studies will lead to a deeper understanding of how telomere dysfunction contributes to lung disease, cancer, and potentially inform rational therapies.